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Predicting host-based, synthetic lethal antiviral targets from omics data
Traditional antiviral therapies often have limited effectiveness due to toxicity and development of drug resistance. Host-based antivirals, while an alternative, may lead to non-specific effects. Recent evidence shows that virus-infected cells can be selectively eliminated by targeting synthetic let...
Autores principales: | Staheli, Jeannette P., Neal, Maxwell L., Navare, Arti, Mast, Fred D., Aitchison, John D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10462099/ https://www.ncbi.nlm.nih.gov/pubmed/37645861 http://dx.doi.org/10.1101/2023.08.15.553430 |
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