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Effects of phosphorylation on Drp1 activation by its receptors, actin, and cardiolipin

Drp1 is a dynamin family GTPase that is required for mitochondrial and peroxisomal division, in which it oligomerizes into a ring and constricts the underlying membrane in a GTP hydrolysis-dependent manner. Oligomerization increases Drp1 GTPase activity through interactions between neighboring GTPas...

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Detalles Bibliográficos
Autores principales: Liu, Ao, Hatch, Anna L., Higgs, Henry N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10462108/
https://www.ncbi.nlm.nih.gov/pubmed/37645886
http://dx.doi.org/10.1101/2023.08.20.554022