Structural Basis for Hyperpolarization-dependent Opening of the Human HCN1 Channel

Hyperpolarization and cyclic-nucleotide (HCN) activated ion channels play a critical role in generating self-propagating action potentials in pacemaking and rhythmic electrical circuits in the human body. Unlike most voltage-gated ion channels, the HCN channels activate upon membrane hyperpolarizati...

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Detalles Bibliográficos
Autores principales: Burtscher, Verena, Mount, Jonathan, Cowgill, John, Chang, Yongchang, Bickel, Kathleen, Yuan, Peng, Chanda, Baron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10462129/
https://www.ncbi.nlm.nih.gov/pubmed/37645882
http://dx.doi.org/10.1101/2023.08.17.553623

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10462129/
https://www.ncbi.nlm.nih.gov/pubmed/37645882
http://dx.doi.org/10.1101/2023.08.17.553623

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