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Mapping the Genetic Interaction Network of PARP inhibitor Response

Genetic interactions have long informed our understanding of the coordinated proteins and pathways that respond to DNA damage in mammalian cells, but systematic interrogation of the genetic network underlying that system has yet to be achieved. Towards this goal, we measured 147,153 pairwise interac...

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Detalles Bibliográficos
Autores principales: Simpson, Danny, Ling, Jia, Jing, Yangwode, Adamson, Britt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10462155/
https://www.ncbi.nlm.nih.gov/pubmed/37645833
http://dx.doi.org/10.1101/2023.08.19.553986