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Evaluation of the RNA-dependence of PRC2 binding to chromatin in human pluripotent stem cells
Polycomb Repressive Complex 2 (PRC2), an important histone modifier and epigenetic repressor, has been known to interact with RNA for almost two decades. In our previous publication (Long, Hwang et al. 2020), we presented data supporting the functional importance of RNA interaction in maintaining PR...
Autores principales: | Long, Yicheng, Hwang, Taeyoung, Gooding, Anne R., Goodrich, Karen J., Vallery, Tenaya K., Rinn, John L., Cech, Thomas R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10462166/ https://www.ncbi.nlm.nih.gov/pubmed/37645830 http://dx.doi.org/10.1101/2023.08.17.553776 |
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