Autistic traits in myotonic dystrophy type 1 due to MBNL inhibition and RNA mis-splicing

Tandem repeat expansions are enriched in autism spectrum disorder, including CTG expansion in the DMPK gene that underlines myotonic muscular dystrophy type 1. Although the clinical connection of autism to myotonic dystrophy is corroborated, the molecular links remained unknown. Here, we show a mech...

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Detalles Bibliográficos
Autores principales: Sznajder, Lukasz, Khan, Mahreen, Tadross, Mariam, Ciesiołka, Adam, Nutter, Curtis, Taylor, Katarzyna, Pearson, Christopher, Sobczak, Krzysztof, Lewis, Mark, Swanson, Maurice, Yuen, Ryan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10462192/
https://www.ncbi.nlm.nih.gov/pubmed/37645891
http://dx.doi.org/10.21203/rs.3.rs-3221704/v1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10462192/
https://www.ncbi.nlm.nih.gov/pubmed/37645891
http://dx.doi.org/10.21203/rs.3.rs-3221704/v1

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