Combination of a MIP3α-antigen fusion therapeutic DNA vaccine with treatments of IFNα and 5-Aza-2’Deoxycytidine enhances activated effector CD8+ T cells expressing CD11c in the B16F10 melanoma model

Previous studies in the B16F10 mouse melanoma model have demonstrated that combining a DNA vaccine comprised of regions of gp100 and tyrosinase-related protein 2 fused to Macrophage-inflammatory protein 3-alpha (MIP3α) with recombinant Interferon alpha (IFN) and 5-Aza-2’-Deoxycytidine (5Aza) treatme...

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Detalles Bibliográficos
Autores principales: Fessler, Kaitlyn, Gordy, James T., Sandhu, Avinaash K., Hui, Yinan, Kapoor, Aakanksha R., Ayeh, Samuel K., Karanika, Styliani, Karakousis, Petros C., Markham, Richard B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10462250/
https://www.ncbi.nlm.nih.gov/pubmed/37645859
http://dx.doi.org/10.21203/rs.3.rs-3243336/v1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10462250/
https://www.ncbi.nlm.nih.gov/pubmed/37645859
http://dx.doi.org/10.21203/rs.3.rs-3243336/v1

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