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Combination of a MIP3α-antigen fusion therapeutic DNA vaccine with treatments of IFNα and 5-Aza-2’Deoxycytidine enhances activated effector CD8+ T cells expressing CD11c in the B16F10 melanoma model

Previous studies in the B16F10 mouse melanoma model have demonstrated that combining a DNA vaccine comprised of regions of gp100 and tyrosinase-related protein 2 fused to Macrophage-inflammatory protein 3-alpha (MIP3α) with recombinant Interferon alpha (IFN) and 5-Aza-2’-Deoxycytidine (5Aza) treatme...

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Detalles Bibliográficos
Autores principales:	Fessler, Kaitlyn, Gordy, James T., Sandhu, Avinaash K., Hui, Yinan, Kapoor, Aakanksha R., Ayeh, Samuel K., Karanika, Styliani, Karakousis, Petros C., Markham, Richard B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Journal Experts 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10462250/ https://www.ncbi.nlm.nih.gov/pubmed/37645859 http://dx.doi.org/10.21203/rs.3.rs-3243336/v1

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