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Tumor cell p38 inhibition to overcome immunotherapy resistance
Patients with tumors that do not respond to immune-checkpoint inhibition often harbor a non-T cell-inflamed tumor microenvironment, characterized by the absence of IFN-γ-associated CD8(+) T cell and dendritic cell activation. Understanding the molecular mechanisms underlying immune exclusion in non-...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Journal Experts
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10462255/ https://www.ncbi.nlm.nih.gov/pubmed/37645831 http://dx.doi.org/10.21203/rs.3.rs-3183496/v1 |