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Mapping high-grade glioma immune infiltration to 5-ALA fluorescence levels: TCGA data computation, classical histology, and digital image analysis

PURPOSE: Resection of high-grade gliomas has been considerably improved by 5-aminolevulinic acid (5-ALA). However, not all neurobiological properties of 5-ALA are fully understood. Specifically, potential differences in immune infiltration have not been conclusively examined, despite recent reports...

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Detalles Bibliográficos
Autores principales: Lang, Alexandra, Jeron, Raphael L., Lontzek, Bastian, Kiesel, Barbara, Mischkulnig, Mario, Berghoff, Anna S., Ricken, Gerda, Wöhrer, Adelheid, Rössler, Karl, Lötsch-Gojo, Daniela, Roetzer-Pejrimovsky, Thomas, Berger, Walter, Hainfellner, Johannes A., Höftberger, Romana, Widhalm, Georg, Erhart, Friedrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10462498/
https://www.ncbi.nlm.nih.gov/pubmed/37543970
http://dx.doi.org/10.1007/s11060-023-04406-3