Preventing mitochondrial reverse electron transport as a strategy for cardioprotection

In the context of myocardial infarction, the burst of superoxide generated by reverse electron transport (RET) at complex I in mitochondria is a crucial trigger for damage during ischaemia/reperfusion (I/R) injury. Here we outline the necessary conditions for superoxide production by RET at complex...

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Detalles Bibliográficos
Autores principales: Prag, Hiran A., Murphy, Michael P., Krieg, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Mitochondria at the Heart of Cardioprotection
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10462584/
https://www.ncbi.nlm.nih.gov/pubmed/37639068
http://dx.doi.org/10.1007/s00395-023-01002-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10462584/
https://www.ncbi.nlm.nih.gov/pubmed/37639068
http://dx.doi.org/10.1007/s00395-023-01002-4

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