Narciclasine, a novel topoisomerase I inhibitor, exhibited potent anti-cancer activity against cancer cells

DNA topoisomerases are essential nuclear enzymes in correcting topological DNA errors and maintaining DNA integrity. Topoisomerase inhibitors are a significant class of cancer chemotherapeutics with a definite curative effect. Natural products are a rich source of lead compounds for drug discovery,...

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Detalles Bibliográficos
Autores principales: Wang, Meichen, Liang, Leilei, Wang, Rong, Jia, Shutao, Xu, Chang, Wang, Yuting, Luo, Min, Lin, Qiqi, Yang, Min, Zhou, Hongyu, Liu, Dandan, Qing, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10462586/
https://www.ncbi.nlm.nih.gov/pubmed/37640882
http://dx.doi.org/10.1007/s13659-023-00392-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10462586/
https://www.ncbi.nlm.nih.gov/pubmed/37640882
http://dx.doi.org/10.1007/s13659-023-00392-1

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