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Narciclasine, a novel topoisomerase I inhibitor, exhibited potent anti-cancer activity against cancer cells
DNA topoisomerases are essential nuclear enzymes in correcting topological DNA errors and maintaining DNA integrity. Topoisomerase inhibitors are a significant class of cancer chemotherapeutics with a definite curative effect. Natural products are a rich source of lead compounds for drug discovery,...
Autores principales: | Wang, Meichen, Liang, Leilei, Wang, Rong, Jia, Shutao, Xu, Chang, Wang, Yuting, Luo, Min, Lin, Qiqi, Yang, Min, Zhou, Hongyu, Liu, Dandan, Qing, Chen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Nature Singapore
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10462586/ https://www.ncbi.nlm.nih.gov/pubmed/37640882 http://dx.doi.org/10.1007/s13659-023-00392-1 |
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