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SOSSB1 and SOSSB2 mutually regulate protein stability through competitive binding of SOSSA

Human single-stranded DNA-binding protein homologs hSSB1 (SOSSB1) and hSSB2 (SOSSB2) make a vital impact on maintaining genome stability as the B subunits of the sensor of single-stranded DNA complex (SOSS). However, whether and how SOSSB1 and SOSSB2 modulate mutual expression is unclear. This study...

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Detalles Bibliográficos
Autores principales: Zhang, Qi, Hao, Rongjiao, Chen, Hongxia, Zhou, Gangqiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10462637/
https://www.ncbi.nlm.nih.gov/pubmed/37640700
http://dx.doi.org/10.1038/s41420-023-01619-3