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Attenuated Salmonella carrying siRNA-PD-L1 and radiation combinatorial therapy induces tumor regression on HCC through T cell-mediated immuno-enhancement

Hepatocellular carcinoma (HCC), the most prevalent type of aggressive liver cancer, accounts for the majority of liver cancer diagnoses and fatalities. Despite recent advancements in HCC treatment, it remains one of the deadliest cancers. Radiation therapy (RT) is among the locoregional therapy moda...

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Detalles Bibliográficos
Autores principales: Jia, Huijie, Wei, Pengkun, Zhou, Shijie, Hu, Yuanyuan, Zhang, Chunjing, Liang, Lirui, Li, Bingqing, Gan, Zerui, Xia, Yuanling, Jiang, Hanyu, Shao, Mingguang, Guo, Sheng, Yang, Zishan, Zhong, Jiateng, Ren, Feng, Zhang, Huiyong, Zhang, Yongxi, Zhao, Tiesuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10462685/
https://www.ncbi.nlm.nih.gov/pubmed/37640735
http://dx.doi.org/10.1038/s41420-023-01603-x