CircRREB1 mediates lipid metabolism related senescent phenotypes in chondrocytes through FASN post-translational modifications

Osteoarthritis is a prevalent age-related disease characterized by dysregulation of extracellular matrix metabolism, lipid metabolism, and upregulation of senescence-associated secretory phenotypes. Herein, we clarify that CircRREB1 is highly expressed in secondary generation chondrocytes and its de...

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Detalles Bibliográficos
Autores principales: Gong, Zhe, Zhu, Jinjin, Chen, Junxin, Feng, Fan, Zhang, Haitao, Zhang, Zheyuan, Song, Chenxin, Liang, Kaiyu, Yang, Shuhui, Fan, Shunwu, Fang, Xiangqian, Shen, Shuying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10462713/
https://www.ncbi.nlm.nih.gov/pubmed/37640697
http://dx.doi.org/10.1038/s41467-023-40975-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10462713/
https://www.ncbi.nlm.nih.gov/pubmed/37640697
http://dx.doi.org/10.1038/s41467-023-40975-7

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