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Plk1 promotes renal tubulointerstitial fibrosis by targeting autophagy/lysosome axis

The prevalence of chronic kidney disease (CKD) has been increasing over the past decades. However, no effective therapies are available for delaying or curing CKD. Progressive fibrosis is the major pathological feature of CKD, which leads to end-stage renal disease (ESRD). The present study showed t...

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Detalles Bibliográficos
Autores principales: Du, Yang, Shang, Yaqiong, Qian, Yun, Guo, Yan, Chen, Shuang, Lin, Xiuli, Cao, Weidong, Tang, Xiaomei, Zhou, Anning, Huang, Songming, Zhang, Aihua, Jia, Zhanjun, Zhang, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10462727/
https://www.ncbi.nlm.nih.gov/pubmed/37640723
http://dx.doi.org/10.1038/s41419-023-06093-4