Chemoenzymatic synthesis of genetically-encoded multivalent liquid N-glycan arrays

Cellular glycosylation is characterized by chemical complexity and heterogeneity, which is challenging to reproduce synthetically. Here we show chemoenzymatic synthesis on phage to produce a genetically-encoded liquid glycan array (LiGA) of complex type N-glycans. Implementing the approach involved...

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Detalles Bibliográficos
Autores principales: Lin, Chih-Lan, Sojitra, Mirat, Carpenter, Eric J., Hayhoe, Ellen S., Sarkar, Susmita, Volker, Elizabeth A., Wang, Chao, Bui, Duong T., Yang, Loretta, Klassen, John S., Wu, Peng, Macauley, Matthew S., Lowary, Todd L., Derda, Ratmir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10462762/
https://www.ncbi.nlm.nih.gov/pubmed/37640713
http://dx.doi.org/10.1038/s41467-023-40900-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10462762/
https://www.ncbi.nlm.nih.gov/pubmed/37640713
http://dx.doi.org/10.1038/s41467-023-40900-y

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