Novel pneumococcal capsule type 33E results from the inactivation of glycosyltransferase WciE in vaccine type 33F

The polysaccharide (PS) capsule is essential for immune evasion and virulence of Streptococcus pneumoniae. Existing pneumococcal vaccines are designed to elicit anticapsule antibodies; however, the effectiveness of these vaccines is being challenged by the emergence of new capsule types or variants....

Descripción completa

Detalles Bibliográficos
Autores principales: Ganaie, Feroze A., Saad, Jamil S., Lo, Stephanie W., McGee, Lesley, van Tonder, Andries J., Hawkins, Paulina A., Calix, Juan J., Bentley, Stephen D., Nahm, Moon H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10462825/
https://www.ncbi.nlm.nih.gov/pubmed/37495106
http://dx.doi.org/10.1016/j.jbc.2023.105085

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10462825/
https://www.ncbi.nlm.nih.gov/pubmed/37495106
http://dx.doi.org/10.1016/j.jbc.2023.105085

Ejemplares similares