mTORC2 orchestrates monocytic and granulocytic lineage commitment by an ATF5-mediated pathway

Myeloid hematopoiesis is a finely controlled consecutive developmental process, which is essential to maintain peripheral innate immune homeostasis. Herein, we found that Rictor deletion caused the remarkable reduction of granulocyte-monocyte progenitors (GMPs), monocytes, and macrophages, while the...

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Detalles Bibliográficos
Autores principales: Zhao, Yang, Zhao, Chenxu, Guo, Han, Zhang, Zhaoqi, Xu, Huawen, Shi, Mingpu, Xu, Yanan, Wei, Dong, Zhao, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10462862/
https://www.ncbi.nlm.nih.gov/pubmed/37649699
http://dx.doi.org/10.1016/j.isci.2023.107540

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10462862/
https://www.ncbi.nlm.nih.gov/pubmed/37649699
http://dx.doi.org/10.1016/j.isci.2023.107540

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