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Incomplete activation of Alyref and Gabpb1 leads to preimplantation arrest in cloned mouse embryos
Differentiated cell nuclei can be reprogrammed after nuclear transfer (NT) to oocytes and the produced NT embryos can give rise to cloned animals. However, development of NT embryos is often hampered by recurrent reprogramming failures, including the incomplete activation of developmental genes, yet...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Life Science Alliance LLC
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10462978/ https://www.ncbi.nlm.nih.gov/pubmed/37640449 http://dx.doi.org/10.26508/lsa.202302296 |