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Incomplete activation of Alyref and Gabpb1 leads to preimplantation arrest in cloned mouse embryos

Differentiated cell nuclei can be reprogrammed after nuclear transfer (NT) to oocytes and the produced NT embryos can give rise to cloned animals. However, development of NT embryos is often hampered by recurrent reprogramming failures, including the incomplete activation of developmental genes, yet...

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Detalles Bibliográficos
Autores principales: Ihashi, Shunya, Hamanaka, Mizuto, Kaji, Masaya, Mori, Ryunosuke, Nishizaki, Shuntaro, Mori, Miki, Imasato, Yuma, Inoue, Kimiko, Matoba, Shogo, Ogonuki, Narumi, Takasu, Atsushi, Nakamura, Misaki, Matsumoto, Kazuya, Anzai, Masayuki, Ogura, Atsuo, Ikawa, Masahito, Miyamoto, Kei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10462978/
https://www.ncbi.nlm.nih.gov/pubmed/37640449
http://dx.doi.org/10.26508/lsa.202302296