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Shared genetic architecture of blood eosinophil counts and asthma in UK Biobank

RATIONALE: Asthma is a complex, heterogeneous disease strongly associated with type 2 inflammation, and blood eosinophil counts guide therapeutic interventions in moderate and severe asthma. Eosinophils are leukocytes involved in type 2 immune responses. Despite these critical associations between a...

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Detalles Bibliográficos
Autores principales: Li, Boyang, Wang, Yuxuan, Wang, Zixiao, Li, Xinyue, Kay, Shannon, Chupp, Geoffrey L., Zhao, Hongyu, Gomez, Jose L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10463033/
https://www.ncbi.nlm.nih.gov/pubmed/37650091
http://dx.doi.org/10.1183/23120541.00291-2023