Secondary bile acids function through the vitamin D receptor in myeloid progenitors to promote myelopoiesis

Metabolic products of the microbiota can alter hematopoiesis. However, the contribution and site of action of bile acids is poorly understood. Here, we demonstrate that the secondary bile acids, deoxycholic acid (DCA) and lithocholic acid (LCA), increase bone marrow myelopoiesis. Treatment of bone m...

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Detalles Bibliográficos
Autores principales: Thompson, Brandon, Lu, Shan, Revilla, Julio, Uddin, Md Jashim, Oakland, David N., Brovero, Savannah, Keles, Sunduz, Bresnick, Emery H., Petri, William A., Burgess, Stacey L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2023
Materias:
Phagocytes, Granulocytes, and Myelopoiesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10463201/
https://www.ncbi.nlm.nih.gov/pubmed/37276450
http://dx.doi.org/10.1182/bloodadvances.2022009618

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10463201/
https://www.ncbi.nlm.nih.gov/pubmed/37276450
http://dx.doi.org/10.1182/bloodadvances.2022009618

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