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Platelet functional abnormalities in pediatric patients with kaposiform hemangioendothelioma/Kasabach-Merritt phenomenon

Kaposiform hemangioendothelioma (KHE) is a rare vascular tumor of infancy that is commonly associated with a life-threatening thrombocytopenic condition, Kasabach-Merritt phenomenon (KMP). Platelet CLEC-2, tumor podoplanin interaction is considered the key mechanism of platelet clearance in these pa...

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Detalles Bibliográficos
Autores principales: Martyanov, Alexey A., Tesakov, Ivan P., Khachatryan, Lili A., An, Olga I., Boldova, Anna E., Ignatova, Anastasia A., Koltsova, Ekaterina M., Korobkin, Julia-Jessica D., Podoplelova, Nadezhda A., Svidelskaya, Galina S., Yushkova, Eugenia, Novichkova, Galina A., Eble, Johannes A., Panteleev, Mikhail A., Kalinin, Dmitrii V., Sveshnikova, Anastasia N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10463204/
https://www.ncbi.nlm.nih.gov/pubmed/37307200
http://dx.doi.org/10.1182/bloodadvances.2022009590