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Application of novel plasma separation filter cards for quantification of nucleoside/nucleotide reverse transcriptase inhibitor di/triphosphates in dried blood spots using LC–MS

BACKGROUND: A rapid and sensitive LC–MS method has been developed and validated for the quantification of nucleoside di/triphosphates using a novel plasma separation card (HemaSep). MATERIALS & METHODS: Cards were spotted with whole blood and stored at -80°C. Metabolites were extracted using 70:...

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Detalles Bibliográficos
Autores principales: Thompson, Beth, Dilly-Penchala, Sujan, Amara, Alieu, Reynolds, Helen, Khoo, Saye, Else, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Newlands Press Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10463213/
https://www.ncbi.nlm.nih.gov/pubmed/37293769
http://dx.doi.org/10.4155/bio-2023-0057