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Flindissone, a Limonoid Isolated from Trichilia prieuriana, Is an LXR Agonist

[Image: see text] In this study, the ability of six limonoids from Trichilia prieuriana (Meliaceae) to activate the liver X receptor (LXR) was assessed. One of these limonoids, flindissone, was shown to activate LXR by reporter-gene assays. Flindissone is a ring-intact limonoid, structurally similar...

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Detalles Bibliográficos
Autores principales: Resetar, Mirta, Tietcheu Galani, Borris R., Tsamo, Armelle T., Chen, Ya, Schachner, Daniel, Stolzlechner, Stefanie, Mawouma Pagna, Julio I., Beniddir, Mehdi A., Kirchmair, Johannes, Dirsch, Verena M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society and American Society of Pharmacognosy 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10463221/
https://www.ncbi.nlm.nih.gov/pubmed/37526502
http://dx.doi.org/10.1021/acs.jnatprod.3c00059