Adverse outcome pathway-based analysis of liver steatosis in vitro using human liver cell lines

Here, we present an in vitro test battery to analyze chemicals for their potential to induce liver triglyceride accumulation, a hallmark of liver steatosis. We describe steps for using HepG2 and HepaRG human hepatoma cells in conjunction with a combination of several in vitro assays covering the dif...

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Detalles Bibliográficos
Autores principales: Karaca, Mawien, Fritsche, Kristin, Lichtenstein, Dajana, Vural, Özlem, Kreuzer, Katrin, Alarcan, Jimmy, Braeuning, Albert, Marx-Stoelting, Philip, Tralau, Tewes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10463250/
https://www.ncbi.nlm.nih.gov/pubmed/37616165
http://dx.doi.org/10.1016/j.xpro.2023.102500

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10463250/
https://www.ncbi.nlm.nih.gov/pubmed/37616165
http://dx.doi.org/10.1016/j.xpro.2023.102500

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