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Adverse outcome pathway-based analysis of liver steatosis in vitro using human liver cell lines
Here, we present an in vitro test battery to analyze chemicals for their potential to induce liver triglyceride accumulation, a hallmark of liver steatosis. We describe steps for using HepG2 and HepaRG human hepatoma cells in conjunction with a combination of several in vitro assays covering the dif...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10463250/ https://www.ncbi.nlm.nih.gov/pubmed/37616165 http://dx.doi.org/10.1016/j.xpro.2023.102500 |