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An unstructured proteasome inhibitor comes into focus
The inhibitory mechanism of an intrinsically disordered proteasome inhibitor identified over 30 years ago has finally been revealed by cryo-electron microscopy by Hsu et al. in a recent report in the Journal of Biological Chemistry. The structure, coupled with biochemical and cell-based experiments,...
Autores principales: | Nemec, Antonia A., Tomko, Robert J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10463253/ https://www.ncbi.nlm.nih.gov/pubmed/37562568 http://dx.doi.org/10.1016/j.jbc.2023.105145 |
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