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C-Terminal Arginine-Selective Cleavage of Peptides as a Method for Mimicking Carboxypeptidase B

[Image: see text] C-Terminal residues play a pivotal role in dictating the structure and functions of proteins. Herein, we report a mild, efficient, chemoselective, and site-selective chemical method that allows for precise chemical proteolysis at C-terminal arginine dictated by 9,10-phenanthrenequi...

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Detalles Bibliográficos
Autores principales: Prosser, Lyndsey C., Talbott, John M., Garrity, Rose P., Raj, Monika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10463270/
https://www.ncbi.nlm.nih.gov/pubmed/37585337
http://dx.doi.org/10.1021/acs.orglett.3c02418