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Pharmacodynamic and pharmacokinetic properties of the combined preparation of levothyroxine plus sustained- release liothyronine; a randomized controlled clinical trial

BACKGROUND: Understanding pharmacokinetics (PK) and pharmacodynamics (PD) of the sustained-release liothyronine (SR-T3) is of paramount importance to design therapeutic regimens that are able to simulate normal thyroid hormone secretion while avoiding excursions in the T3 serum concentration. Here,...

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Detalles Bibliográficos
Autores principales: Mehran, Ladan, Amouzegar, Atieh, Foroutan, Seyed Mohsen, Masoumi, Safdar, Tohidi, Maryam, Abdi, Hengameh, Aghaei, Ali, Saghafinia, Amir Esmaeel, Azizi, Fereidoun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10463362/
https://www.ncbi.nlm.nih.gov/pubmed/37641049
http://dx.doi.org/10.1186/s12902-023-01434-y