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Design, synthesis, in vitro anticancer, molecular docking and SAR studies of new series of pyrrolo[2,3-d]pyrimidine derivatives

The current study involves the design and synthesis of a newly synthesized pyrrolo[2,3-d]pyrimidine derivatives to contain chlorine atoms in positions 4 and 6 and trichloromethyl group in position 2 using microwave technique as a new and robust approach for preparation of this type of pyrrolo[2,3-d]...

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Detalles Bibliográficos
Autores principales: Sroor, Farid M., Tohamy, Wael M., Zoheir, Khairy M. A., Abdelazeem, Nagwa M., Mahrous, Karima F., Ibrahim, Nada S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10463376/
https://www.ncbi.nlm.nih.gov/pubmed/37641068
http://dx.doi.org/10.1186/s13065-023-01014-0