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IL-25 induces airway remodeling in asthma by orchestrating the phenotypic changes of epithelial cell and fibrocyte

BACKGROUND: Previous studies have shown that IL-25 levels are increased in patients with asthma with fixed airflow limitation (FAL). However, the mechanism by which IL-25 contributes to airway remodeling and FAL remains unclear. Here, we hypothesized that IL-25 facilitates pro-fibrotic phenotypic ch...

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Detalles Bibliográficos
Autores principales: Yao, Xiujuan, Chen, Qinglin, Wang, Xiangdong, Liu, Xiaofang, Zhang, Luo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10463650/
https://www.ncbi.nlm.nih.gov/pubmed/37635231
http://dx.doi.org/10.1186/s12931-023-02509-z