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AGEs promote atherosclerosis by increasing LDL transcytosis across endothelial cells via RAGE/NF-κB/Caveolin-1 pathway

OBJECTIVE: To elucidate the mechanism whereby advanced glycation end products (AGEs) accelerate atherosclerosis (AS) and to explore novel therapeutic strategies for atherosclerotic cardiovascular disease. METHODS AND RESULTS: The effect of AGEs on low-density lipoprotein (LDL) transcytosis across en...

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Detalles Bibliográficos
Autores principales: Shu, Meng, Cheng, Wenzhuo, Jia, Xiong, Bai, Xiangli, Zhao, Ying, Lu, Yajing, Zhu, Lin, Zhu, Yan, Wang, Li, Shu, Yan, Song, Yi, Jin, Si
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10463687/
https://www.ncbi.nlm.nih.gov/pubmed/37605109
http://dx.doi.org/10.1186/s10020-023-00715-5