Pimobendan prevents cardiac dysfunction, mitigates cardiac mitochondrial dysfunction, and preserves myocyte ultrastructure in a rat model of mitral regurgitation

BACKGROUND: Pimobendan has been proven to delay the onset of congestive heart failure (CHF) in dogs with mitral regurgitation (MR); however, molecular underlying mechanisms have not been fully elucidated. This study aimed to investigate (1) the effects of pimobendan on cardiac function, cardiac mito...

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Detalles Bibliográficos
Autores principales: Boonpala, Pakit, Saengklub, Nakkawee, Srikam, Sirinapa, Ji-au, Wilawan, Panyasing, Yaowalak, Kumphune, Sarawut, Kijtawornrat, Anusak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10463781/
https://www.ncbi.nlm.nih.gov/pubmed/37612694
http://dx.doi.org/10.1186/s12917-023-03693-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10463781/
https://www.ncbi.nlm.nih.gov/pubmed/37612694
http://dx.doi.org/10.1186/s12917-023-03693-2

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