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A cysteine proteinase inhibitor ALLN alleviates bleomycin-induced skin and lung fibrosis

BACKGROUND: Systemic sclerosis (SSc) is a connective tissue disease that is characterized by fibrosis in the skin and internal organs, such as the lungs. Activated differentiation of progenitor cells, which are mainly resident fibroblasts, into myofibroblasts is considered a key mechanism underlying...

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Detalles Bibliográficos
Autores principales: Kasamatsu, Hiroshi, Chino, Takenao, Hasegawa, Takumi, Utsunomiya, Natsuko, Utsunomiya, Akira, Yamada, Masami, Oyama, Noritaka, Hasegawa, Minoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10463804/
https://www.ncbi.nlm.nih.gov/pubmed/37626391
http://dx.doi.org/10.1186/s13075-023-03130-7