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Regulation and clinical potential of telomerase reverse transcriptase (TERT/hTERT) in breast cancer

Telomerase reverse transcriptase (TERT/hTERT) serves as the pivotal catalytic subunit of telomerase, a crucial enzyme responsible for telomere maintenance and human genome stability. The high activation of hTERT, observed in over 90% of tumors, plays a significant role in tumor initiation and progre...

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Detalles Bibliográficos
Autores principales: Yang, Ruozhu, Han, Yi, Guan, Xinyu, Hong, Yue, Meng, Jiahao, Ding, Shirong, Long, Qian, Yi, Wenjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10463831/
https://www.ncbi.nlm.nih.gov/pubmed/37612721
http://dx.doi.org/10.1186/s12964-023-01244-8