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Regulation and clinical potential of telomerase reverse transcriptase (TERT/hTERT) in breast cancer
Telomerase reverse transcriptase (TERT/hTERT) serves as the pivotal catalytic subunit of telomerase, a crucial enzyme responsible for telomere maintenance and human genome stability. The high activation of hTERT, observed in over 90% of tumors, plays a significant role in tumor initiation and progre...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10463831/ https://www.ncbi.nlm.nih.gov/pubmed/37612721 http://dx.doi.org/10.1186/s12964-023-01244-8 |