Comprehensive analyses of partially methylated domains and differentially methylated regions in esophageal cancer reveal both cell-type- and cancer-specific epigenetic regulation

BACKGROUND: As one of the most common malignancies, esophageal cancer has two subtypes, squamous cell carcinoma and adenocarcinoma, arising from distinct cells-of-origin. Distinguishing cell-type-specific molecular features from cancer-specific characteristics is challenging. RESULTS: We analyze who...

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Detalles Bibliográficos
Autores principales: Zheng, Yueyuan, Ziman, Benjamin, Ho, Allen S., Sinha, Uttam K., Xu, Li-Yan, Li, En-Min, Koeffler, H Phillip, Berman, Benjamin P., Lin, De-Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10463844/
https://www.ncbi.nlm.nih.gov/pubmed/37620896
http://dx.doi.org/10.1186/s13059-023-03035-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10463844/
https://www.ncbi.nlm.nih.gov/pubmed/37620896
http://dx.doi.org/10.1186/s13059-023-03035-3

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