PPARγ activation suppresses chondrocyte ferroptosis through mitophagy in osteoarthritis

BACKGROUND: Osteoarthritis (OA) is a prevalent disease plaguing the elderly. Recently, chondrocyte ferroptosis has been demonstrated to promote the progression of OA. Peroxisome proliferator-activated receptor-γ (PPARγ) is an important factor in maintaining cartilage health. However, the relationshi...

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Detalles Bibliográficos
Autores principales: Xue, Xiang, Dai, Tianming, Chen, Junyan, Xu, Yangyang, Yang, Zhenyu, Huang, Jian, Xu, Wuyan, Li, Siming, Meng, Qingqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10463860/
https://www.ncbi.nlm.nih.gov/pubmed/37620972
http://dx.doi.org/10.1186/s13018-023-04092-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10463860/
https://www.ncbi.nlm.nih.gov/pubmed/37620972
http://dx.doi.org/10.1186/s13018-023-04092-x

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