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PPARγ activation suppresses chondrocyte ferroptosis through mitophagy in osteoarthritis

BACKGROUND: Osteoarthritis (OA) is a prevalent disease plaguing the elderly. Recently, chondrocyte ferroptosis has been demonstrated to promote the progression of OA. Peroxisome proliferator-activated receptor-γ (PPARγ) is an important factor in maintaining cartilage health. However, the relationshi...

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Detalles Bibliográficos
Autores principales:	Xue, Xiang, Dai, Tianming, Chen, Junyan, Xu, Yangyang, Yang, Zhenyu, Huang, Jian, Xu, Wuyan, Li, Siming, Meng, Qingqi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10463860/ https://www.ncbi.nlm.nih.gov/pubmed/37620972 http://dx.doi.org/10.1186/s13018-023-04092-x

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