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α-Synuclein-carrying astrocytic extracellular vesicles in Parkinson pathogenesis and diagnosis

BACKGROUND: The accumulation of α-synuclein (α-syn), an essential step in PD development and progression, is observed not only in neurons but also in glia, including astrocytes. The mechanisms regulating astrocytic α-syn level and aggregation remain unclear. More recently, it has been demonstrated t...

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Detalles Bibliográficos
Autores principales: Wang, Pan, Lan, Guoyu, Xu, Bin, Yu, Zhenwei, Tian, Chen, Lei, Xia, Meissner, Wassilios G., Feng, Tao, Yang, Ying, Zhang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10463943/
https://www.ncbi.nlm.nih.gov/pubmed/37620916
http://dx.doi.org/10.1186/s40035-023-00372-y