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RNF173 suppresses RAF/MEK/ERK signaling to regulate invasion and metastasis via GRB2 ubiquitination in Hepatocellular Carcinoma

BACKGROUND: The role of the membrane-associated RING-CH (MARCH) family in carcinogenesis has been widely studied, but the member of this family, RNF173, has not yet been thoroughly explored in the context of hepatocellular carcinoma (HCC). METHODS: With the use of an HCC tissue microarray and IHC st...

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Detalles Bibliográficos
Autores principales: Zhou, Jie, Tu, Daoyuan, Peng, Rui, Tang, Yuhong, Deng, Qiangwei, Su, Bingbing, Wang, Shunyi, Tang, Hao, Jin, Shengjie, Jiang, Guoqing, Wang, Qian, Jin, Xin, Zhang, Chi, Cao, Jun, Bai, Dousheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10464048/
https://www.ncbi.nlm.nih.gov/pubmed/37626338
http://dx.doi.org/10.1186/s12964-023-01241-x