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Quantification of transcriptome changes to investigate the role of glucocorticoid receptor-RNA binding during dexamethasone treatment

OBJECTIVES: The glucocorticoid receptor (GR) is a well-studied, ligand-activated transcription factor and a common target of anti-inflammatory treatments. Recently, several studies have drawn attention the effects of binding of GR to RNA rather than DNA and the potential implications of this activit...

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Detalles Bibliográficos
Autores principales: Lammer, Nickolaus C., Allen, Mary A., Batey, Robert T., Wuttke, Deborah S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10464093/
https://www.ncbi.nlm.nih.gov/pubmed/37608297
http://dx.doi.org/10.1186/s13104-023-06446-4