Cargando…

SCA: recovering single-cell heterogeneity through information-based dimensionality reduction

Dimensionality reduction summarizes the complex transcriptomic landscape of single-cell datasets for downstream analyses. Current approaches favor large cellular populations defined by many genes, at the expense of smaller and more subtly defined populations. Here, we present surprisal component ana...

Descripción completa

Detalles Bibliográficos
Autores principales: DeMeo, Benjamin, Berger, Bonnie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10464206/
https://www.ncbi.nlm.nih.gov/pubmed/37626411
http://dx.doi.org/10.1186/s13059-023-02998-7