A multi-functional hypoxia/esterase dual stimulus responsive and hyaluronic acid-based nanomicelle for targeting delivery of chloroethylnitrosouea

Carmustine (BCNU), a vital type of chloroethylnitrosourea (CENU), inhibits tumor cells growth by inducing DNA damage at O(6) position of guanine and eventually forming dG-dC interstrand cross-links (ICLs). However, the clinical application of BCNU is hindered to some extent by the absence of tumor s...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Duo, Ren, Ting, Ge, Yunxuan, Wang, Xiaoli, Sun, Guohui, Zhang, Na, Zhao, Lijiao, Zhong, Rugang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10464291/
https://www.ncbi.nlm.nih.gov/pubmed/37612719
http://dx.doi.org/10.1186/s12951-023-02062-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10464291/
https://www.ncbi.nlm.nih.gov/pubmed/37612719
http://dx.doi.org/10.1186/s12951-023-02062-3

Ejemplares similares