Reevaluation of bromodomain ligands targeting BAZ2A

BAZ2A promotes migration and invasion in prostate cancer. Two chemical probes, the specific BAZ2‐ICR, and the BAZ2/BRD9 cross‐reactive GSK2801, interfere with the recognition of acetylated lysines in histones by the bromodomains of BAZ2A and of its BAZ2B paralog. The two chemical probes were tested...

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Detalles Bibliográficos
Autores principales: Cazzanelli, Giulia, Vedove, Andrea Dalle, Parolin, Eleonora, D'Agostino, Vito Giuseppe, Unzue, Andrea, Nevado, Cristina, Caflisch, Amedeo, Lolli, Graziano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10464297/
https://www.ncbi.nlm.nih.gov/pubmed/37574751
http://dx.doi.org/10.1002/pro.4752

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10464297/
https://www.ncbi.nlm.nih.gov/pubmed/37574751
http://dx.doi.org/10.1002/pro.4752

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