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Reevaluation of bromodomain ligands targeting BAZ2A
BAZ2A promotes migration and invasion in prostate cancer. Two chemical probes, the specific BAZ2‐ICR, and the BAZ2/BRD9 cross‐reactive GSK2801, interfere with the recognition of acetylated lysines in histones by the bromodomains of BAZ2A and of its BAZ2B paralog. The two chemical probes were tested...
Autores principales: | Cazzanelli, Giulia, Vedove, Andrea Dalle, Parolin, Eleonora, D'Agostino, Vito Giuseppe, Unzue, Andrea, Nevado, Cristina, Caflisch, Amedeo, Lolli, Graziano |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10464297/ https://www.ncbi.nlm.nih.gov/pubmed/37574751 http://dx.doi.org/10.1002/pro.4752 |
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