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Calcineurin stimulation by Cnb1p overproduction mitigates protein aggregation and α-synuclein toxicity in a yeast model of synucleinopathy

The calcium-responsive phosphatase, calcineurin, senses changes in Ca(2+) concentrations in a calmodulin-dependent manner. Here we report that under non-stress conditions, inactivation of calcineurin signaling or deleting the calcineurin-dependent transcription factor CRZ1 triggered the formation of...

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Detalles Bibliográficos
Autores principales:	Chawla, Srishti, Ahmadpour, Doryaneh, Schneider, Kara L., Kumar, Navinder, Fischbach, Arthur, Molin, Mikael, Nystrom, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Brief Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10464345/ https://www.ncbi.nlm.nih.gov/pubmed/37620860 http://dx.doi.org/10.1186/s12964-023-01242-w

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