CRISPR/Cas13d targeting GZMA in PARs pathway regulates the function of osteoclasts in chronic apical periodontitis

Chronic apical periodontitis is a prevalent oral disease characterized by bone loss, and its underlying mechanisms remain unclear. This study aimed to investigate the role and mechanism of the serine protease GZMA in osteoclasts during chronic apical periodontitis. To address this, we employed crRNA...

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Detalles Bibliográficos
Autores principales: Jia, Tingting, Yuan, Fang, Tao, Jingqiao, Wang, Gang, Zhang, Xianhua, Zhang, Bin, Li, Hongbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10464397/
https://www.ncbi.nlm.nih.gov/pubmed/37626297
http://dx.doi.org/10.1186/s11658-023-00477-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10464397/
https://www.ncbi.nlm.nih.gov/pubmed/37626297
http://dx.doi.org/10.1186/s11658-023-00477-2

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