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Amorphous silica nanoparticles cause abnormal cytokinesis and multinucleation through dysfunction of the centralspindlin complex and microfilaments

BACKGROUND: With the large-scale production and application of amorphous silica nanoparticles (aSiNPs), its adverse health effects are more worthy of our attention. Our previous research has demonstrated for the first time that aSiNPs induced cytokinesis failure, which resulted in abnormally high in...

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Detalles Bibliográficos
Autores principales: Xiao, Liyan, Pang, Jinyan, Qin, Hua, Dou, Liyang, Yang, Man, Wang, Ji, Zhou, Xianqing, Li, Yang, Duan, Junchao, Sun, Zhiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10464468/
https://www.ncbi.nlm.nih.gov/pubmed/37608338
http://dx.doi.org/10.1186/s12989-023-00544-8